過去・私たちの医学研究

川又教授の資格 (active 現在活動中, [inactive 現在活動なし])
医師免許 active
内科専門医 active
総合内科専門医 active
血液専門医 active 
[米国 医師免許 inactive]
[米国 遺伝子病専門医 inactive]
川又教授の所属学会
日本内科学会 active
日本血液学会 評議員 active
日本造血細胞療法学会 active
日本臨床検査学会 active 
米国 アメリカ血液学会 正国際学会員 active
米国 アメリカ癌研究学会 正国際学会員 active
[米国 アメリカ遺伝子病学会 正会員 inactive]
学術活動 
投稿論文査読 英文医学雑誌 Blood, Leukemia, British J. Haematology, International J. Hematology
       日本語医学雑誌 臨床血液
受賞歴
1994年 内藤財団若手研究者奨励賞(大阪)
2002年 東京医科歯科大学 医科同窓会 若手研究者奨励賞 (東京)
2007年 タワー癌研究財団 若手研究者奨励賞(ロサンゼルス)
2008年 ルース L. キルシュスタイン 臨床医・研究医奨励賞(ロサンゼルス)
2009年 スポーツ・スペクタキュラー研究奨励賞 (ロサンゼルス)
業績(英文)(査読付き科学雑誌論文 筆頭著者論文19本 最終著者論文2本 総論文数73本 )
(2023年3月現在) 筆頭著者 総インパクト・ファクター(IF)  全論文 総インパクト・ファクター
1. Kawamata N, Miki T, Ohashi K, Suzuki K, Fukuda T, Hirosawa S, Aoki N. Recognition DNA sequence of a novel putative transcription factor, BCL6. Biochem Biophys Res Commun. 1994: 204: 366-74. (IF 2.705)
2 . Kawamata N, Miki T, Fukuda T, Hirosawa S, Aoki N. The organization of the BCL6 gene. Leukemia. 1994: 8: 1327-30. (IF 9.944) 博士論文
3. Suzuki K, Miki T, Kawamata N, Hirosawa S, Yoshizawa K, Kiyosawa K, Aoki N. Variant translocation of the BCL6 gene to immunoglobulin kappa light chain gene in B-cell lymphoma. Jpn J Cancer Res. 1994: 85: 911-7. (IF 4.890)
4. Miki T, Kawamata N, Hirosawa S, Aoki N. Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Kruppel-like zinc-finger protein. Blood. 1994. 83: 26-32. (IF 16.562)
5. Miki T, Kawamata N, Arai A, Ohashi K, Nakamura Y, Kato A, Hirosawa S, Aoki N. Molecular cloning of the breakpoint for 3q27 translocation in B-cell lymphomas and leukemias. Blood. 1994: 83: 217-22. (IF 16.562)
6. Koyama T, Hirosawa S, Kawamata N, Tohda S, Aoki N. All-trans retinoic acid upregulates thrombomodulin and downregulates tissue-factor expression in acute promyelocytic leukemia cells: distinct expression of thrombomodulin and tissue factor in human leukemic cells. Blood. 1994: 84: 3001-9. (IF 16.562)
7. Kawamata N, Miller CW, Koeffler HP. Molecular analysis of a family of cyclin-dependent kinase inhibitor genes (p15/MTS2/INK4b and p18/INK4c) in non-small cell lung cancers. 1995: Mol Carcinog. 14: 263-8. (IF 3.411)
8. Morosetti R, Kawamata N, Gombart AF, Miller CW, Hatta Y, Hirama T, Said JW, Tomonaga M, Koeffler HP. Alterations of the p27KIP1 gene in non-Hodgkin's lymphomas and adult T-cell leukemia/lymphoma. 1995: Blood. 86: 1924-30. (IF 16.562)
9: Nakamura Y, Miki T, Kawamata N, Hirosawa S, Saito K, Enokihara H, Furusawa S, Shishido H. Biallelic DNA rearrangements and deletions within the BCL-6 gene in B-cell non-Hodgkin's lymphoma. Br J Haematol. 1995: 90: 404-8. (IF 5.206)
10. Kawamata N, Morosetti R, Miller CW, Park D, Spirin KS, Nakamaki T, Takeuchi S, Hatta Y, Simpson J, Wilcyznski S, Koeffler HP. Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. 1995: Cancer Res. 55: 2266-9. (IF 8.378)
11. Kawamata N, Park D, Wilczynski S, Yokota J, Koeffler HP. Point mutations of the Mxil gene are rare in prostate cancers. Prostate. 1996. 29: 191-3. (IF 2.876)
12. Spirin KS, Simpson JF, Takeuchi S, Kawamata N, Miller CW, Koeffler HP. p27/Kip1 mutation found in breast cancer. 1996: Cancer Res. 56: 2400-4. (IF 8.378)
13. Kawamata N, Miller C, Levy V, Shintaku IP, Koeffler HP, Said JW. mdm-2 oncogene expression in non-Hodgkin's lymphomas. Diagn Mol Pathol. 1996. 5: 33-8. (IF )
14. Kawamata N, Seriu T, Koeffler HP, Bartram CR. Molecular analysis of the cyclin-dependent kinase inhibitor family: p16(CDKN2/MTS1/INK4A), p18(INK4C) and p27(Kip1) genes in neuroblastomas. Cancer. 1996: 77: 570-5. (IF 6.102)
15. Kawamata N, Seriu T, Bartram CR, Koeffler HP. Molecular analysis of the secretory phospholipase A2 gene, a candidate of Mom1 gene, in neuroblastomas. Cancer Lett. 1997: 111:71-5. (IF 6.508)
16. Verbeek W, Spirin K, Hatta Y, Miller C, Kawamata N, Takeuchi S, Koike M, Asou H, Simpson J, Koeffler H. DPC 4/SMAD 4 in non-pancreatic tumors with frequent LOH 18q21 and in hematological malignancies. Int J Oncol. 1997: 10: 257-60. (IF 3.571)
17. Kawamata N, Nakamura Y, Miki T, Sato E, Isobe Y, Furusawa S, Hirosawa S, Oshimi K. Detection of chimaeric transcripts of the immunoglobulin heavy chain and BCL6 genes by reverse-transcriptase polymerase chain reaction in B-cell non-Hodgkin's lymphomas. Br J Haematol. 1998: 100: 484-9. (IF 5.206)
18. Egashira M, Kawamata N, Sugimoto K, Kaneko T, Oshimi K. P-glycoprotein expression on normal and abnormally expanded natural killer cells and inhibition of P-glycoprotein function by cyclosporin A and its analogue, PSC833. Blood. 1999: 93: 599-606. (IF 16.562)  筆頭著者博士論文
19. Sato E, Kawamata N, Kato A, Oshimi K. A novel mutation that leads to a congenital factor XI deficiency in a Japanese family. Am J Hematol.2000. 63: 165-9. (IF 6.137) 筆頭著者博士論文
20. Sakajiri S, Kawamata N, Egashira M, Mori K, Oshimi K. Molecular analysis of tumor suppressor genes, Rb, p53, p16INK4A, p15INK4B and p14ARF in natural killer cell neoplasms. Jpn J Cancer Res. 2001. 92: 1048-56. (IF 4.890)  筆頭著者博士論文
21. Sugimoto KJ, Kawamata N, Sakajiri S, Oshimi K. Molecular analysis of oncogenes, ras family genes (N-ras, K-ras, H-ras), myc family genes (c-myc, N-myc) and mdm2 in natural killer cell neoplasms. Jpn J Cancer Res. 2002: 93: 1270-7. (IF 4.890)  筆頭著者博士論文
22. Kawamata N, Sakajiri S, Sugimoto KJ, Isobe Y, Kobayashi H, Oshimi K. A novel chromosomal translocation t(1;14)(q25;q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4. 2002. Oncogene. 21: 4983-91. (IF 6.634)
23. Kato A, Kawamata N, Tamayose K, Egashira M, Miura R, Fujimura T, Murayama K, Oshimi K. Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3. J Biol Chem. 2002: 277: 28934-41. (IF 4.106)
24. Sakajiri S, Mori K, Isobe Y, Kawamata N, Oshimi K. Epstein-Barr virus-associated T-cell acute lymphoblastic leukaemia. Br J Haematol. 2002: 117: 127-9. 2002 (IF 5.206)
25. Mori N, Yang R, Kawamata N, Miller CW, Mizoguchi H, Koeffler HP. Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors. 2003: Int J Hematol. 77: 259-62. (IF 2.251)
26.(# co-first authors) #Takai N, #Kawamata N, Gui D, Said JW, Miyakawa I, Koeffler HP. Human ovarian carcinoma cells: histone deacetylase inhibitors exhibit antiproliferative activity and potently induce apoptosis. Cancer. 2004: 101: 2760-70. (IF 6.102)
27. Sakajiri S, Kumagai T, Kawamata N, Saitoh T, Said J, Koeffler HP. Histone deacetylase inhibitors profoundly decrease proliferation of human lymphoid cancer cell lines. Exp Hematol. 2005: 33: 53-61. (IF 2.462)
28. Kawamata N, Mizumura S, Inagaki N, Sugimoto K-J, Sakajiri S, Ohyanagi-Hara M, Oshimi K. Methylation status analysis of cell cycle regulatory genes (p16INK4A, p15INK4B, p21Waf1/Cip1, p27Kip1 and p73) in natural killer cell disorders. Eur J Haematol. 2005: 74: 424-9. 2005 (IF 2.217)
29. (# co-first author) #Takai N, #Kawamata N, Walsh CS, Gery S, Desmond JC, Whittaker S, Said JW, Popoviciu LM, Jones PA, Miyakawa I, Koeffler HP. Discovery of epigenetically masked tumor suppressor genes in endometrial cancer. Mol Cancer Res. 2005: 3: 261-9. 2005 (IF 4.484)
30. Kawamata N, Sugimoto KJ, Sakajiri S, Oshimi K, Koeffler HP. Novel isoforms of Mxi1 genes are expressed in hematopoietic cell lines and normal bone marrows. Mxi1 isoforms are expressed in hematological cell lines and normal bone marrow. Int J Oncol. 2005: 26: 1369-75. (IF 3.571)
31. Sakajiri S, O'kelly J, Yin D, Miller CW, Hofmann WK, Oshimi K, Shih LY, Kim KH, Sul HS, Jensen CH, Teisner B, Kawamata N, Koeffler HP. Dlk1 in normal and abnormal hematopoiesis. Leukemia. 2005: 19: 1404-10. (IF 9.944)
32. Takai N, Jain A, Kawamata N, Popoviciu LM, Said JW, Whittaker S, Miyakawa I, Agus DB, Koeffler HP. 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth. Cancer. 2005: 104: 2701-8. (IF 6.102)
33. Komatsu N, Kawamata N, Takeuchi S, Yin D, Chien W, Miller CW, Koeffler HP. SAHA, a HDAC inhibitor, has profound anti-growth activity against non-small cell lung cancer cells. Oncol Rep. 2006: 15: 187-91. (IF 3.014)
34. Yin D, Ong JM, Hu J, Desmond JC, Kawamata N, Konda BM, Black KL, Koeffler HP. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of glioma cells in vitro and in vivo. Clin Cancer Res. 2007: 13: 1045-52. (IF 8.911)
34. Gery S, Komatsu N, Kawamata N, Miller CW, Desmond J, Virk RK, Marchevsky A, Mckenna R, Taguchi H, Koeffler HP. Epigenetic silencing of the candidate tumor suppressor gene Per1 in non-small cell lung cancer. Clin Cancer Res. 2007: 13: 1399-404. (IF 8.911)
35. Kumagai T, Wakimoto N, Yin D, Gery S, Kawamata N, Takai N, Komatsu N, Chumakov A, Imai Y, Koeffler HP. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. Int J Cancer. 2007: 121: 656-65. (IF 4.982)
36. Yamamoto G, Nannya Y, Kato M, Sanada M, Levine RL, Kawamata N, Hangaishi A, Kurokawa M, Chiba S, Gilliland DG, Koeffler HP, Ogawa S. Highly sensitive method for genomewide detection of allelic composition in nonpaired, primary tumor specimens by use of affymetrix single-nucleotide-polymorphism genotyping microarrays. Am J Hum Genet. 2007: 81: 114-26. (IF 9.924)
37. Kawamata N, Chen J, Koeffler HP. Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells. Blood. 2007: 110: 2667-73. (IF 16.562)
38. Gery S, Gueller S, Chumakova K, Kawamata N, Liu L, Koeffler HP. Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders. Blood. 2007: 110: 3360-4. (IF 16.562)
39. Muller CI, Miller CW, Hofmann WK, Gross ME, Walsh CS, Kawamata N, Luong QT, Koeffler HP. Rare mutations of the PIK3CA gene in malignancies of the hematopoietic system as well as endometrium, ovary, prostate and osteosarcomas, and discovery of a PIK3CA pseudogene. Leuk Res. 2007. 31: 27-32. (IF 2.351)
40. Kawamata N, Ogawa S, Zimmermann M, Kato M, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR, Koeffler HP. Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray. Blood. 2008: 111: 776-84. (IF 16.562)
41. Lehmann S, Ogawa S, Raynaud SD, Sanada M, Nannya Y, Ticchioni M, Bastard C, KawamataN, Koeffler HP. Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia. Cancer. 2008: 112: 1296-305. (IF 6.102)
42. Walsh CS, Ogawa S, Karahashi H, Scoles DR, Pavelka JC, Tran H, Miller CW, Kawamata N, Ginther C, Dering J, Sanada M, Nannya Y, Slamon DJ, Koeffler HP, Karlan BY. ERCC5 is a novel biomarker of ovarian cancer prognosis. J Clin Oncol. 2008: 26: 2952-8. (IF 28.245)
43. Kawamata N, Ogawa S, Zimmermann M, Niebuhr B, Stocking C, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR, Koeffler HP. Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray. Proc Natl Acad Sci U S A. 2008: 105: 11921-6. (IF 9.580)
44. Kawamata N, Ogawa S, Yamamoto G, Lehmann S, Levine RL, Pikman Y, Nannya Y, Sanada M, Miller CW, Gilliland DG, Koeffler HP. Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray. Exp Hematol. 2008: 36: 1471-9. (IF 2.462)
45. Walsh CS, Ogawa S, Scoles DR, Miller CW, Kawamata N, Narod SA, Koeffler HP, Karlan BY. Genome-Wide Loss of Heterozygosity and Uniparental Disomy in BRCA1/2-Associated Ovarian Carcinomas. Clin Cancer Res. 2008: 14: 7645-7651. (IF 8.911)
46. Akagi T, Ogawa S, Dugas M, Kawamata N, Yamamoto G, Nannya Y, Sanada M, Miller CW, Yung A, Schnittger S, Haferlach T, Haferlach C, Koeffler HP. Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotype. Haematologica. 2009: 94: 213-23. (IF 7.570)
47. Akagi T, Shih LY, Kato M, Kawamata N, Yamamoto G, Sanada M, Okamoto R, Miller CW, Liang DC, Ogawa S, Koeffler HP. Hidden abnormalities and novel classification of t(15;17) APL based on genomic alterations. Blood. 2009: 113: 1741-8. (IF 16.562)
48. Akagi T, Yin D, Kawamata N, Bartram CR, Hofmann WK, Song JH, Miller CW, den Boer ML, Koeffler HP. Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells. Leuk Res2009: 33: 991-6. (IF 2.066)
49. Kawamata N, Ogawa S, Seeger K, Kirschner-Schwabe R, Huynh T, Chen J, Megrabian N, Harbott J, Zimmermann M, Henze G, Schrappe M, Bartram CR, Koeffler HP. Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia. Int J Oncol 2009: 34: 1603-12. (IF 3.571)
50. Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S. Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. Nature. 2009: 460: 904-8. (IF 43.070)
51. Nowak D, Le Toriellec E, Stern MH, Kawamata N, Akagi T, Dyer MJ, Hofmann WK, Ogawa S, Koeffler HP. Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy. Haematologica. 2009: 94: 518-27. (IF 7.570)
52. Yin D, Ogawa S, Kawamata N, Tunici P, Finocchiaro G, Eoli M, Ruckert C, Huynh T, Liu G, Kato M, Sanada M, Jauch A, Dugas M, Black KL, Koeffler HP. High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray. Mol Cancer Res. 2009: 7: 665-77. (IF 4.484)
53. Kawamata N, Ogawa S, Gueller S, Ross SH, Huynh T, Chen J, Chang A, Nabavi-Nouis S, Megrabian N, Siebert R, Martinez-Climent JA, Koeffler HP. Identified hidden genomic changes in mantle cell lymphoma using high-resolution single nucleotide polymorphism genomic array. Exp Hematol. 2009: 37: 937-46. (IF 2.462)
54. Akagi T, Ito T, Kato M, Jin Z, Cheng Y, Kan T, Yamamoto G, Olaru A, Kawamata N, Boult J, Soukiasian HJ, Miller CW, Ogawa S, Meltzer SJ, Koeffler HP. Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma. Int J Cancer. 2009: 125: 2349-59. (IF 4.982)
55. Akagi T, Shih LY, Ogawa S, Gerss J, Moore SR, Schreck R, Kawamata N, Liang DC, Sanada M, Nannya Y, Deneberg S, Zachariadis V, Nordgren A, Song JH, Dugas M, Lehmann S, Koeffler HP. Single nucleotide polymorphism genomic arrays analysis of t(8;21) acute myeloid leukemia cells. Haematologica. 2009: 94: 1301-6. (IF 7.570)
56. Kumagai T, Akagi T, Desmond JC, Kawamata N, Gery S, Imai Y, Song JH, Gui D, Said J, Koeffler HP. Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells. Int J Cancer. 2009: 124: 827-33. (IF 4.982)
57: Lilljebjörn H, Soneson C, Andersson A, Heldrup J, Behrendtz M, Kawamata N,Ogawa S, Koeffler HP, Mitelman F, Johansson B, Fontes M, Fioretos T. The correlation pattern of acquired copy number changes in 164 ETV6/RUNX1-positive childhood acute lymphoblastic leukemias. Hum Mol Genet. 2010: 19: 3150-8. (IF 4.544)
58. Sherborne AL, Hosking FJ, Prasad RB, Kumar R, Koehler R, Vijayakrishnan J, Papaemmanuil E, Bartram CR, Stanulla M, Schrappe M, Gast A, Dobbins SE, Ma Y, Sheridan E, Taylor M, Kinsey SE, Lightfoot T, Roman E, Irving JA, Allan JM, Moorman AV, Harrison CJ, Tomlinson IP, Richards S, Zimmermann M, Szalai C, Semsei AF, Erdelyi DJ, Krajinovic M, Sinnett D, Healy J, Gonzalez Neira A, Kawamata N, Ogawa S, Koeffler HP, Hemminki K, Greaves M, Houlston RS. Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Nat Genet. 2010: 42: 492-4. (IF 25.455)
59. Okamoto R, Ogawa S, Nowak D, Kawamata N, Akagi T, Kato M, Sanada M, Weiss T, Haferlach C, Dugas M, Ruckert C, Haferlach T, Koeffler HP. Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia. Haematologica. 2010: 95: 1481-8. (IF 7.570)
60. Thoennissen NH, Krug UO, Lee DH, Kawamata N, Iwanski GB, Lasho T, Weiss T, Nowak D, Koren-Michowitz M, Kato M, Sanada M, Shih LY, Nagler A, Raynaud SD, Müller-Tidow C, Mesa R, Haferlach T, Gilliland DG, Tefferi A, Ogawa S, Koeffler HP. Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms. Blood. 2010: 115: 2882-90. (IF 16.562)
61. Nowak D, Ogawa S, Müschen M, Kato M, Kawamata N, Meixel A, Nowak V, Kim HS, Kang S, Paquette R, Chang MS, Thoennissen NH, Mossner M, Hofmann WK, Kohlmann A, Weiss T, Haferlach T, Haferlach C, Koeffler HP. SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations. Blood. 2010: 115: 1049-53. (IF 16.562)
62. Kawamata N, Pennella MA, Woo JL, Berk AJ, Koeffler HP. Dominant-negative mechanism of leukemogenic PAX5 fusions. 2012: Oncogene. 31 :966-77. 2012 (IF 6.634)
63. Yin D, Ogawa S, Kawamata N, Leiter A, Ham M, Li D, Doan NB, Said JW, Black KL, Phillip Koeffler H. miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme. Oncogene. 2013: 32:1155-63. (IF 6.634)
64. Kawamata N, Moreilhon C, Saitoh T, Karasawa M, Bernstein BK, Sato-Otsubo A, Ogawa S, Raynaud S, Koeffler HP. Genetic differences between Asian and Caucasian chronic lymphocytic leukemia. Int J Oncol. 2013: 43: 561-5. (IF 3.571)
65. Hayano T, Garg M, Yin D, Sudo M, Kawamata N, Shi S, Chien W, Ding LW, Leong G, Mori S, Xie D, Tan P, Koeffler HP. SOX7 is down-regulated in lung cancer. J Exp Clin Cancer Res. 2013: 32: 17. (IF 5.646)
66. Costa-Guda J, Imanishi Y, Palanisamy N, Kawamata N, Phillip Koeffler H, Chaganti RS, Arnold A. Allelic imbalance in sporadic parathyroid carcinoma and evidence for its de novo origins. Endocrine. 2013: 44:489-495. (IF 3.296)
67. Nowak D, Liem NL, Mossner M, Klaumünzer M, Papa RA, Nowak V, Jann JC, Akagi T, Kawamata N, Okamoto R, Thoennissen NH, Kato M, Sanada M, Hofmann WK, Ogawa S, Marshall GM, Lock RB, Koeffler HP. Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance. Exp Hematol. 2015: 43: 32-43. (IF 2.462)
68. Ding LW, Sun QY, Tan KT, Chien W, Mayakonda A, Yeoh AEJ, Kawamata N, Nagata Y, Xiao JF, Loh XY, Lin DC, Garg M, Jiang YY, Xu L, Lim SL, Liu LZ, Madan V, Sanada M, Fernández LT, Hema Preethi SS, Lill M, Kantarjian HM, Kornblau SM, Miyano S, Liang DC, Ogawa S, Shih LY, Yang H, Koeffler HP. Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia. Cancer Res. 2017: 77: 390-400. (IF 8.378)
69. Xie J, Lin D, Lee DH, Akunowicz J, Hansen M, Miller C, Sanada M, Kato M, Akagi T, Kawamata N, Ogawa S, Koeffler HP. Copy number analysis identifies tumor suppressive lncRNAs in human osteosarcoma. Int J Oncol. 2017: 50: 863-872. (IF 3.571 )
70. Izumi Y, Kanayama M, Shen Z, Kai M, Kawamura S, Akiyama M, Yamamoto M, Nagao T, Okada K, Kawamata N, Toyota S, Ohteki T. An Antibody-Drug Conjugate That Selectively Targets Human Monocyte Progenitors for Anti-Cancer Therapy. Front Immunol. 2021: 12:618081. (IF 6.429)
71. Yasuda S, Aoyama S, Yoshimoto R, Li H, Watanabe D, Akiyama H, Yamamoto K, Fujiwara T, Najima Y, Doki N, Sakaida E, Edahiro Y, Imai M, Araki M, Komatsu N, Miura O, Kawamata N. MPL overexpression induces a high level of mutant-CALR/MPL complex: a novel mechanism of ruxolitinib resistance in myeloproliferative neoplasms with CALR mutations. Int J Hematol. 2021: 114: 424-440. (IF 2.251)
72. Yasuda S, Najima Y, Konishi T, Yamada Y, Nagata A, Takezaki T, Kaito S, Kurosawa S, Sakaguchi M, Harada K, Shingai N, Yoshioka K, Inamoto K, Mukae J, Toya T, Igarashi A, Shimizu H, Kobayashi T, Kakihana K, Sakamaki H, Kawamata N, Ohashi K, Doki N. Outcome of allogeneic hematopoietic stem cell transplantation for T-cell lymphoblastic leukemia/lymphoma: A single-center study. Leuk Res. 2021: 108:106627. (if 2.066) 筆頭著者博士論文
73. Aoyama S, Yasuda S, Li H, Watanabe D, Umezawa Y, Okada K, Nogami A, Miura O, Kawamata N. A novel chimeric antigen receptor (CAR) system using an exogenous protease, in which activation of T cells is controlled by expression patterns of cell‑surface proteins on target cells. Int J Mol Med. 2022 Apr;49(4):42. (IF 5.314) 筆頭著者博士論文