Top> 研究業績（2013年以前）

学術論文・総説など

2013年以前

  1. "Design and applications of artificial restriction DNA cutters for site-selective scission of genomes"
    M. Komiyama, J. Sumaok, Bull. Chem. Soc. Jpn., 2012, 85, 533-544.
  2. "Sensitive RNA detection by combining three-way junction formation and primer generation-rolling circle amplification",
    T. Murakami, J. Sumaoka, M. Komiyama, Nucleic Acids Res., 2012, 40, e22.
  3. "Artificial DNA Cutters for DNA Manipulation and Genome Engineering",
    Y. Aiba, J. Sumaoka, M. Komiyama, Chem. Soc. Rev., 2011, 40, 5657-5668.
  4. "スーパー制限酵素を用いた遺伝子改変（高分子科学最近の進歩）",
    須磨岡淳, 鴫成実, 小宮山眞, 高分子, 2011, 60, 203-208.
  5. "Oxidation of an oligonucleotide-bound Ce(III)/multiphosphonate complex for site-selective DNA scission". T. Lönnberg, Y. Aiba, Y. Hamano, Y. Miyajima, J. Sumaoka, M. Komiyama, Chem. Eur. J., 2010, 16, 855-859.
  6. "Binuclear Terbium(III) Complex as a Probe for Tyrosine Phosphorylation",
    H. Akiba, J. Sumaoka, M. Komiyama, Chem. Eur. J., 2010, 16, 5018-5025.
  7. "Molecular Imprinting of Cyclodextrin to Physiologically Active Oligopeptides in Water",
    S. H. Song, K. Shirasaka, Y. Hirokawa, H. Asanuma, T. Wada, J. Sumaoka, M. Komiyama, Supramol. Chem., 2010, 22, 149-155.
  8. "水系で生体分子を認識するインプリント高分子",
    須磨岡淳, 小宮山眞, 高分子論文集, 2009, 66, 191-201
  9. "希土類錯体のバイオテクノロジーへの応用",
    須磨岡淳, 希土類, 2009, 55, 1-12.
  10. "Efficient Guest Inclusion by beta-Cyclodextrin Attached to the Ends of DNA Oligomers upon Hybridization to Various DNA Conjugates",
    A. Kuzuya, T. Ohnishi, T. Wasano, S. Nagaoka, J. Sumaoka, T. Ihara, A. Jyo, M. Komiyama, Bioconjugate Chem., 2009, 20, 1643-1649.
  11. "Selective Detection of Phosphotyrosine among Various Phosphate-containing Biomolecules by Terbium(III) Complex",
    H. Akiba, J. Sumaoka, M. Komiyama, ChemBioChem, 2009, 10 , 1773-1776.
  12. "Origin of High Fidelity in Target-Sequence Recognition by PNA Ce(IV)/EDTA Combinations as Site-Selective DNA Cutters",
    Y. Miyajima, T. Ishizuka, Y. Yamamoto, J. Sumaoka, M. Komiyama, J. Am. Chem. Soc., 2009, 131 , 2657-2662
  13. "Strand Invasion of Conventional PNA to Arbitrary Sequence in DNA Assisted by Single-Stranded DNA Binding Protein",
    T. Ishizuka, K. Otani, J. Sumaoka, M. Komiyama, Chem. Commun., 2009, 1225-1227.
  14. "Sensitive Isothermal Detection of Nucleic-Acid Sequence by Primer Generation-Rolling Circle Amplification",
    T. Murakami, J. Sumaoka, M. Komiyama, Nucleic Acids Res., 2009, 37, e19.
  15. "Artificial restriction DNA cutter for site-selective scission of double-stranded DNA with tunable scission-site and specificity",
    M. Komiyama, Y. Aiba, Y. Yamamoto, and J. Sumaoka, Nature Protoc., 2009, 3, 655-664.
  16. "Solid-phase synthesis of pseudo-complementary peptide nucleic acids",
    M. Komiyama, Y. Aiba, T. Ishizuka, and J. Sumaoka, Nature Protoc., 2009, 3, 646-654.
  17. "Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences",
    T. Ishizuka, J. Yoshida, Y. Yamamoto, J. Sumaoka, T. Tedeschi, R. Corradini, S. Sforza, and M. Komiyama, Nucleic Acids Res., 2008, 36, 1464-1471.
  18. "Reconfirmation of recognition site in composites of imprinted beta-cyclodextrin polymer/solid support as stationary phase of HPLC",
    S. Nagaoka, S.H. Song, J. Sumaoka, M. Komiyama, Chem. Lett., 2008, 37, 1148-1149.
  19. "Crystal structure of Ce(IV)/dipicolinate complex as catalyst for DNA hydrolysis",
    H. Katada, H. Seino, Y. Mizobe, J. Sumaoka, and M. Komiyama, J. Biol. Inorg. Chem., 2008, 13, 249-255
  20. "Specific recognition by molecularly imprinted cyclodextrins – from small molecules to biological macromolecules (Minireview)",
    S. Song, J. Sumaoka, and M. Komiyama, Fourth Asian Cyclodextrin Conference (ACC2007), 42-47.
  21. "Artificial Restriction DNA Cutters (ARCUT) for Future Biotechnology",
    J. Sumaoka, Y. Yamamoto, Y. Kitamura, and M. Komiyama, Curr. Org. Chem., 2007, 11, 463-475.
  22. "希土類のバイオテクノロジーへの応用",
    須磨岡淳, 化学工業, 2007, 58(10), 22-30
  23. "DNAを自在に切断するスーパー制限酵素の開発",
    須磨岡淳, 小宮山眞, 現代化学, 2007, No.436，32-39.
  24. "Recognition of Solution Structures of Peptides by Molecularly Imprinted Cyclodextrin Polymers",
    S. Song, K. Shirasaka, M. Katayama, S. Nagaoka, S. Yoshihara, T. Osawa, J. Sumaoka, H. Asanuma, and M. Komiyama, Macromolecules, 2007, 40, 3530-3532.
  25. "Fabrication of Au-DNA-Au nanostructure with new-type DNA-Au conjugate",
    Fenggang Pan, Jun Sumaoka, Toshiyuki Hirano, Yoshitaka Hokutsu, Osamu Takkeuchi, Hidemi Shigekawa, and Makoto Komiyama, Nucleic Acids, Symp. Ser., 2006, 50, 317-318.
  26. "Oligonucleotide-bound Eu(III) as a probe for microenvironments at specific site in DNA",
    J. Sumaoka, Y. Kojima, and M. Komiyama, Chem. Lett., 2006, 35, 930-931.
  27. "Recombination of the GFP gene to the BFP gene using a man-made site-selective DNA cutter",
    Y. Kitamura, S. Mori, W. Chen, J. Sumaoka, and M. Komiyama, J. Biol. Inorg. Chem., 2006, 11, 13-16.
  28. "Application of cerium(IV)/EDTA complex for future biotechnology",
    J. Sumaoka, W. Chen, Y. Kitamura, T. Tomita, J. Yoshida, and M. Komiyama, J. Alloys Compd., 2006, 408, 391-395.
  29. "Active species for Ce(IV)-induced hydrolysis of phosphodiester linkage in cAMP and DNA",
    J. Sumaoka K. Furuki, Y. Kojima M. Shibata, K. Hirao, N. Takada, M. Komiyama, Nucleosides, Nucleotides Nucleic Acid, 2006, 25, 523-538.
  30. "Site-selective DNA Hydrolysis by Combining Ce(IV)/EDTA with Monophosphate-bearing Oligonucleotides and Enzymatic Ligation of the Scission Fragments",
    W. Chen, Y. Kitamura, J-M. Zhou, J. Sumaoka, and M. Komiyama, J. Am. Chem. Soc., 2004, 126, 10285-10291.
  31. "Direct attachment of double-stranded DNA to gold surface for preparation of nano-structured devices",
    J. Sumaoka FG. Pan, A. Nonaka, O. Takeuchi, H. Shigekawa and M. Komiyama, Chem. Lett., 2004, 33 700-701.
  32. "Monophosphate as eminent ligand to bind Ce(IV)/EDTA complex for site-selective DNA hydrolysis",
    W. Chen, J. Sumaka, and M. Komiyama, Chem. Lett., 2004, 33 300-301.
  33. "セリウムを用いるバイオサイエンス",
    須磨岡淳, マテリアルインテグレーション, 2003, 16，No.2，30-36
  34. "Cerium(IV)/EDTA Complex for DNA Hydrolysis",
    Y. Kitamura, J. Sumaoka, and M. Komiyama, Tetrahedron, 2003, 59, 10403-10408.
  35. "Formation Process of Cyclodextrin Necklace-Analysis of Hydrogen Bonding on a Molecular Level",
    K. Miyake, S. Yasuda, A. Harada, J. Sumaoka, M.Komiyama, and H. Shigekawa, J. Am. Chem. Soc., 2003, 125, 5080-5085.
  36. "Effect of complexes coordinating alginic polysaccharides with cerium on cleavage of plasmid DNA and bovine serum albumin",
    D. Wang, J. Sumaoka, C. Wang, X. Liang, M. Komiyama, Zhongguo Xitu Xuebao, 2002, 20, 283-285.
  37. "Remarkable cooperativity between a Zn-II ion and guanidinium/ammonium groups in the hydrolysis of RNA",
    H. Ait-Haddou, J. Sumaoka, S.L. Wiskur, J.F. Folmer-Andersen, and E. Anslyn, Angew. Chem. Int. Ed., 2002, 41, 4014-4016
  38. "A trinuclear copper(II) complex showing high selectivity for the hydrolysis of 2’→5’ over 3’→5’ for UpU and 3’→5’ over 2’→5’ for ApA ribonucleotides",
    M. Komiyama, S. Kina, K. Matsumura, J. Sumaoka, S. Tobey, V. M. Lynch, and E. Anslyn, J. Am. Chem. Soc., 2002, 124, 13731-13736
  39. "Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA",
    K. Matsumura, S. Kina, J. Sumaoka, S. Tobey, E. Anslyn, and M. Komiyama, Nucleic Acids Res. Supple., 2001, 1, 85-86
  40. "Monolayer formation of 6-deosy-6-thiol-a-cyclodextrin on a Au(111) surface studied by scanning tunneling microscopy",
    S. Yasuda, D. N. Futaba, O Takeuchi, I Suzuki, K. Yase, J. Sumaoka, M. Komiyama, and H. Shigekawa, J. Vac. Sci. Technol. A, 2001, 19(4), 1266-1269
  41. "Interactive force between cyclodextrin inclusion complexes studied by atomic force microscopy",
    S. Oyama, K. Miyake, S. Yasuda, O. Takeuchi, J. Sumaoka, M. Komiyama, D.N. Futaba, T. Morita, M. Yamashita, and H. Shigekawa, Jpn. J. Appl. Phys., 2001, 40, 4419-4422.
  42. "Cooperation of Ce(IV)/EDTA complex and oligoamine for prompt scission of DNA",
    T. Igawa, J. Sumaoka, and M. Komiyama, Chem. Lett., 2001, 20-21
  43. "Hydrolysis of DNA by Ce(IV)/EDTA complexes -The mechanism of DNA cleavage and design of artificial restriction enzymes",
    Y. Yamamoto, T. Igawa, J. Sumaoka, and M. Komiyama, Nucleic Acids, Symp. Ser., 2000, 44, 231-232
  44. "Manipulation of cyclodextrin necklace. -The molecular abacus-",
    H. Shigekawa, K. Miyake, J. Sumaoka, A. Harada, and M. Komiyama, J. Am. Chem. Soc., 2000, 122, 5411-5412.
  45. "Kinetic Studies on Ce(IV)-Induced Hydrolysis of Single-Stranded and Double-Stranded Oligonucleotides",
    T. Igawa, J. Sumaoka, and M. Komiyama, Nucleotides, Nucleosides, and Nucleic Acids, 2000, 19, 891-902.
  46. "Hydrolysis of Oligonucleotides by Homogeneous Ce(IV)/EDTA Complex",
    T. Igawa, J. Sumaoka, and M. Komiyama, Chem. Lett., 2000, 356-357.
  47. "Homogeneous Ce(IV) Complexes for Efficient Hydrolysis of Plasmid DNA",
    T. Igawa, K. Furuki, J. Sumaoka, and M. Komiyama, Chem. Lett., 2000, 56-57.
  48. "Improvement of efficiency of the Ce(IV)-induced DNA scission  -Relationship between the kinetic parameters (kcat and Km) and the DNA structure",
    T. Igawa, J. Sumaoka, and M. Komiyama, Nucleic Acids, Symp Ser., 1999, 42, 231-232.
  49. "Effect of the dipole-dipole interaction on the self-assembly of cyclodextrin inclusion complexes",
    S. Yasuda, K. Miyake, J. Sumaoka, M. Komiyama, and H. Shigekawa, Jpn. J. Appl. Phys., 1999, 38, 3888-3891.
  50. "Extended x-ray absorption fine structure study on the cerium(IV)-induced DNA hydrolysis. -Implication to the roles of 4f orbitals in the catalysis",
    H. Shigekawa, M. Ishida, K. Miyake, R. Shioda, Y. Iijima, T. Imai, H. Takahashi, J. Sumaoka, and M. Komiyama, Appl. Phys. Lett., 1999, 74, 460-462.
  51. "Photo-regulation of RNA hydrolysis by the zinc(II) complex carrying azobenzene",
    J. Sumaoka, K. Kawata, and M. Komiyama, Chem. Lett., 1999, 439-440
  52. "DNA hydrolysis by Ce(IV) involves the cooperation of two metal ions",
    J. Sumaoka, N. Takeda, Y. Okada, H. Takahashi, H. Shigekawa, and M. Komiyama, Nucleic Acids, Symp. Ser., 1998, 39, 137-138
  53. "Progress towards Synthetic Enzymes for Phosphoester Hydrolysis",
    M. Komiyama and J. Sumaoka, Curr. Opin. Chem. Biol., 1998, 2, 751-757.
  54. "Scanning tunneling microscopy on ordered self-assemblies of cyclodextrin inclusion complexes formed by substrate-induced two-dimensional crystal growth",
    S. Yasuda, K. Miyake, Y. Goto, M. Ishida, K. Hata, M. Fujita, M. Yoshida, J. Sumaoka, M. Komiyama, and H. Shigekawa, Jpn. J. Appl. Phys., 1998, 37, 3844-3848
  55. "DNA hydrolysis by the complexes between Ce(IV) ion and saccharides",
    A. Kajimura, J. Sumaoka, and M. Komiyama, Carbohydr. Res., 1998, 309, 345-351
  56. "Enzymatic manipulation of the fragments obtained by cerium (IV)-induced DNA scission: Characterization of hydrolytic termini",
    J. Sumaoka, Y. Azuma, and M. Komiyama, Chem. Eur. J., 1998, 4, 205-209
  57. "RNA hydrolysis by cobalt(III) complexes",
    M. Komiyama, Y. Matsumoto, H. Takahashi, T. Shiiba, H. Tsuzuki, H. Yajima, M. Yashiro, and J. Sumaoka, J. Chem. Soc., Perkin Trans. 2, 1998, 691-695
  58. "Cerium(IV)/lanthanide(III)/dextran ternary solutions for efficient and homogeneous DNA hydrolysis",
    J. Sumaoka, A. Kajimura, T. Imai, M. Ohno, and M. Komiyama, Nucleosides and Nucleotides, 1998, 17, 613-623.
  59. "Efficient RNA hydrolysis by lanthanide(III)-hydrogen peroxide combinations. Novel aggregates as the catalytic species",
    J. Kamitani, J. Sumaoka, H. Asanuma, and M. Komiyama, J. Chem. Soc., Perkin Trans. 2, 1998, 523-527.
  60. "DNA and RNA hydrolysis by metal complexes for artificial pin-point restriction enzymes",
    M. Komiyama, M. Yashiro, A. Ishikubo, A. Kajimura, M. Ohno, and J. Sumaoka, J. Inorg. Biochem., 1997, 67(1-4), 341
  61. "Homogeneous metal complexes for DNA hydrolysis and their application to artificial restriction enzymes",
    J. Sumaoka, A. Kajimura, M. Ohno, and M. Komiyama, J. Inorg. Biochem., 1997, 67(1-4), 361
  62. "Homogeneous catalyst for DNA hydrolysis (4). Efficient DNA hydrolysis by lanthanide-saccharide complexes",
    J. Sumaoka, A. Kajimura, and M. Komiyama, Nucleic Acids, Symp. Ser., 1997, 37, 211-212
  63. "Totally man-made enzymes for pinpoint and hydrolytic scission of DNA and RNA",
    M. Komiyama, J. Sumaoka, and M. Yashiro, FASEB J., 1997, 11, A1286.
  64. "Homogeneous DNA hydrolysis by cerium(IV)/lanthanide(III)/dextran ternary complexes",
    J. Sumaoka, A. Kajimura, M. Ohno, and M. Komiyama, Chem. Lett., 1997, 507-508
  65. "Structure-reactivity relationship for the Co(III) complex-catalysed hydrolysis of adenosine 3',5'-cyclic monophosphate",
    M. Komiyama, J. Sumaoka, K. Yonezawa, Y. Matsumoto, and M. Yashiro, J. Chem. Soc., Perkin Trans. 2, 1997, 75-78.
  66. "RNA hydrolysis by lanthanide/H2O2 systems.",
    J. Kamitani, J. Sumaoka, H. Asanuma, and M. Komiyama, Nucleic Acids, Symp. Ser., 1996, 35, 141-142.
  67. "Enormous cooperative catalyses of two metal ions for the hydrolysis of adenosine 3',5'-cyclic monophosphate",
    H. Yajima, J. Sumaoka, and M. Komiyama, Nucleic Acids, Symp. Ser., 1996, 35, 139-140
  68. "Core level photoelectron spectroscopy on the lanthanide-induced hydrolysis of DNA",
    H. Shigekawa, H. Ikawa, R. Yoshizaki, Y. Iijima, J. Sumaoka, and M. Komiyama, Appl. Phys. Lett., 1996, 68, 1433-1435
  69. "RNA hydrolysis by the combination of lanthanum(III) ion and hydrogen peroxide",
    M. Komiyama, J. Kamitani, J. Sumaoka, and H. Asanuma, Chem. Lett.,  1996, 869-870.
  70. "Unprecedentedly fast DNA hydrolysis by the synergism of the cerium(IV) - praseodymium(III) and cerium(IV) - neodymium(III) combinations",
    N. Takeda, T. Imai, M. Irisawa, J. Sumaoka, M. Yashiro, H. Shigekawa, and M. Komiyama, Chem. Lett., 1996, 599-600.
  71. "Acetylacetonato - lanthanide complexes as eminent catalytic sites for artificial ribonucleases",
    J. Sumaoka, H. Uchida, and M. Komiyama, Nucleic Acids, Symp. Ser., 1995, 34, 83-84.
  72. "次世代バイオテクノロジーへの新戦略 －スーパー制限酵素の構築－",
    須磨岡淳, 小宮山眞, 機能材料, 1995, 15(6), 19-25.
  73. "Lanthanide ions for the first non-enzymatic formation of adenosine 3',5'-cyclic monophosphate from adenosine triphospate under physiological conditions",
    H. Yajima, J. Sumaoka, S. Miyama, and M. Komiyama, J. Biochem., 1994, 115, 1038-1039.
  74. "Catalytically active species for the CeCl3-induced DNA hydrolysis",
    M. Komiyama, T. Kodama, N. Takeda, J. Sumaoka, T. Shiiba, Y. Matsumoto, and M. Yashiro, J. Biochem., 1994, 115, 809-810.
  75. "DNA hydrolysis by cerium(IV) does not involve either molecular oxygen or hydrogen peroxide",
    M. Komiyama, T. Shiiba, T. Kodama, N. Takeda, J. Sumaoka, and M. Yashiro, Chem. Lett.,   1994, 1025-1028.
  76. "Enormous acceleration by cerium(IV) for the hydrolysis of nucleoside 3',5'-cyclic monophosphates at pH 7",
    J. Sumaoka, S. Miyama, and M. Komiyama, J. Chem. Soc., Chem. Commun., 1994, 1755-1756.
  77. "ランタニド(III)イオンによる生体内リン酸ジエステル化合物の効率的加水分解",
    小宮山眞, 八代盛夫, 松本洋一, 須磨岡淳, 松村一成, 日本化学会誌, 1993, 5, 411-417.
  78. "Mutual isomerization of adenosine 2'- and 3'-phosphates by tris(3-aminopropyl) aminecobalt(III)",
    J. Sumaoka, T. Shiiba, and M. Komiyama, J. Mol. Catal., 1993, 78, L53-L56.
  79. "Enormous catalyses of lanthanide metal ions for unprecedentedly fast hydrolysis of 3',5'-cyclic adenosine monophosphate",
    J. Sumaoka, M. Yashiro, and M. Komiyama, Nucleic Acids, Symp. Ser., 1992, 27, 37-38
  80. "Remarkably fast hydrolysis of 3',5'-cyclic adenosine monophosphate by cerium(III) hydroxide cluster ",
    J. Sumaoka, M. Yashiro, and M. Komiyama, J. Chem. Soc., Chem. Commun., 1992, 1707-1708.

著書など

2013年以前

  1. "Covalent and non-covalent conjugates of oligonucleotide as artificial restriction DNA cutters",
    M. Komiyama, Y. Xu, J. Sumaoka, RSC Biomolecular Sciences No.26, DNA Conjugates and Sensors, 278-295, RSC Publishihg (2012).
  2. "Artificial Restriction DNA Cutters (ARCUT) as New Tools to Manipulate Human Genome",
    J.Sumaoka, M. Komiyama, Advancies in Biomedical Research (Proceedings of the International Conference on Biochemistry, and Medical  Chemistry (BIOTECH '10)), 485-489 (2012).
  3. "スーパー人工制限酵素",
    小宮山眞, 須磨岡淳, 酵素 利用技術体系, 小宮山眞編, 370-375, エヌ・ティー・エス （2010）.
  4. "Sensitive Nucleic Acid Detection by Primer Generation-Rolling Circle Amplifcation",
    T. Murakami, J. Sumaoka, M. Komiyama, EPICENTRE Forum Newsletter, 16, 7-9 (2009)
  5. "遺伝子切断",
    須磨岡淳, 葛谷明紀, 小宮山眞, 化学フロンティア 5「生命化学のニューセントラルドグマ」, 44-53, 化学同人 （2002）.
  6. "Sequence-Selective Artificial Ribonucleases",
    M. Komiyama, J. Sumaoka, A. Kuzuya, and Y. Yamamoto, Methods in Enzymology, J.N. Abelson and I. Simon ed., 341, 455-468, Academic Press (2001).
  7. "希土類イオンと糖類との錯体形成とその応用",
    小宮山眞, 須磨岡淳, 季刊化学総説No48, 「糖鎖分子の設計と生理機能」, 129-135, 学会出版センター （2001）.
  8. "人工制限酵素"
    小宮山眞, 須磨岡淳, 葛谷明紀, バイオミメティックスハンドブック、編集代表 長田義人、298-304、エヌ・ティー・エス（2000）.